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St. Catharines (2006 population 131,989; metropolitan population 390,317) is the largest city in the Niagara Region in southern Ontario, Canada, with 97.11 square kilometres (37.5 sq mi) of land. It lies 51 kilometres (32 mi) south of Toronto across Lake Ontario and is 19 kilometres (12 mi) inland from the international boundary with the United States of America along the Niagara River. It is the northern entrance of the Welland Canal. Residents of St. Catharines are known as St. Catharinites.